US 11,767,314 B2 · Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same

Abstract

New nicotinic acid glycerol ester compound(s) (NAEs); topical personal care compositions containing NAEs; and methods for modulating or activating cellular AMPK levels; and for increasing skin cellular bioenergetics are described. Use of one or more of the nicotinic acid glycerol ester compounds for modulating or activating cellular AMPK levels; and for increasing skin cellular bioenergetics are described. Use of a skin benefit agent comprising certain nicotinic acid glycerol ester compounds in the manufacture of a topical personal care composition for modulating or activating cellular AMPK levels; and for increasing skin cellular bioenergetics are described.

Claims14

Dependent claims

A nicotinic acid glycerol ester compound consisting of:

a. Structural Formula IV
wherein R1 and R2 are independently C1-C5 linear, branched or cyclic alkyl;
saturated or unsaturated;
with or without a heteroatom;
including salts thereof.

2 more elements

Dependencies are inferred from the claim text.

Facts

Application

17/288,173Filed 29 Oct 2019

Priority

EP 182042032 Nov 2018

Published

US 2021/0380564 A19 Dec 2021

Granted

26 Sep 2023

Term ends

Not estimatedThe source records don’t support an estimate.

Classification11 codes

C07D 405/12
Containing two hetero rings: linked by a chain containing hetero atoms as chain links
A61K 8/062
Emulsions: oil-in-water emulsions
A61K 8/4926
With one nitrogen as the only hetero atom: having six membered rings
A61K 31/44
Having six-membered rings with one nitrogen as the only ring hetero atom: non condensed pyridines; Hydrogenated derivatives thereof

Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same

Life of this patent

Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same

Life of this patent

Abstract

Claims14