Method for producing amine through reduction of amide

A method for producing a primary amine and a secondary amine, comprising:

• reducing a primary amide or a secondary amide in the presence of an organometallic halide of a Group 2 element and a reducing agent, wherein
• the primary amide or the secondary amide is an amide represented by the following formula (1):
• wherein R1 and R2 each independently represent hydrogen, an alkyl group, a cycloalkyl group, an aryl group, an aralkyl group, a heterocyclic group, an alkenyl group, an alkynyl group, a cycloalkenyl group, an alkyloxy group, a cycloalkyloxy group, an aryloxy group, an aralkyloxy group, a hydroxyl group, an alkoxycarbonyl group, a cycloalkyloxycarbonyl group, an aryloxycarbonyl group, an aralkyloxycarbonyl group, an alkenyloxycarbonyl group, an alkynyloxycarbonyl group, or a cycloalkenyloxycarbonyl group, each of which optionally have a substituent;
• and R1 and R2 together may form a ring, and
• the primary amine and the secondary amine are amines represented by the following formula (2):
• wherein R1 and R2 mean the same as above, and
• the organometallic halide of the Group 2 element is a Grignard reagent, and
• the reducing agent is a borohydride-based reagent or sodium bis(2-methoxyethoxy)aluminum hydride.