Treating degenerative dementia with low intensity focused ultrasound pulsation (LIFUP) device

One or more non-transitory computer-readable media (NTCRM) having instructions, stored thereon, that when executed by one or more processors, cause an ultrasonic transducer to:

• generate a focused ultrasonic beam;
• and
• direct the focused ultrasonic beam at a target area of a brain of a patient, wherein the focused ultrasonic beam includes a plurality of groups of pulses, wherein individual groups of pulses of the plurality of groups of pulses include multiple individual pulses, wherein the individual groups of pulses are repeated at a rate between 1-4 Hertz to stimulate a deep sleep patient episode, and wherein a first time period between individual pulses of a respective individual group of pulses of the plurality of groups of pulses is less than a second time period between the respective individual group of pulses and a next individual group of pulses of the plurality of groups of pulses.

A method comprising:

• attaching an ultrasonic transducer to a head of a patient;
• operating the ultrasonic transducer to apply a focused ultrasonic beam that is focused at a target area of the brain, wherein the focused ultrasonic beam includes a plurality of groups of pulses, and wherein the plurality of groups of pulses are repeated at a pulse rate between 1-4 Hertz to stimulate a deep sleep patient episode, and wherein the focused ultrasonic beam is applied to the target area after the patient has taken a norepinephrine blocker to inhibit norepinephrine.