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US 11,766,473 B2Granted
Therapeutic cancer vaccine containing tumor-associated neoantigens and immunostimulants in a deliver system
AssigneeXeme Biopharma Inc.
InventorsMircea C. Popescu, Richard J. Robb
Life of this patent
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Abstract
A therapeutic vaccine and a method of cancer treatment by inducing humoral and cellular immune responses against malignant cells is provided. The vaccine comprises a delivery system that incorporates at least one peptide whose sequence encompasses a genetic mutation associated with a malignancy (neoantigen), at least one immunostimulant, and at least one type of lipid molecule.
Claims8
A therapeutic cancer vaccine comprising:
- at least one neoantigen, wherein the neoantigen comprises a tumor-associated genetic mutation peptide, and wherein the tumor-associated genetic mutation peptide further includes a tryptophan attachment element consisting of NRWIT (SEQ ID NO:2);
- at least one immunostimulant;
- and
- at least one type of lipid molecule.
1 more element
Dependencies are inferred from the claim text.