Cyclopentathiophene carboxamide derivatives as platelet activating factor receptor antagonists

A compound of formula (I.1)

• wherein
• R1 is selected from the group consisting of C1-4-alkyl optionally substituted with 1 to 3 F and of C3-4-cycloalkyl;
• R2 is selected from the group consisting of F, Cl, Br, I, C1-4-alkyl, C3-4-cycloalkyl, —CN, —CONH2, —CONH(C1-4-alkyl), —CON(C1-4-alkyl)2, —COOH, —COO—C1-4-alkyl, OH, —O—C1-4-alkyl, and S(O)r—C1-4-alkyl with r=0, 1, or 2;
• wherein
• the C1-4-alkyl R2 group may be optionally substituted with 1 to 3 F or optionally substituted with 1 —CN, with 1 OH, or with 1 —O—C1-4-alkyl, and
• the —O—C1-4-alkyl R2 group may be optionally substituted with 1 to 3 F;
• n is selected from the group consisting of 0, 1, 2, and 3;
• R3 and R4, together with the amide N atom they are attached to, form a heterocyclyl selected from the group consisting of
• or a pharmaceutically acceptable salt thereof.