Composition for preventing or treating dry eye syndrome containing α-humulene as active ingredient
AssigneeInje University Industry-Academic Cooperation Foundation
InventorsHyo-Jong Lee, Su Jung Hwang
Life of this patent
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Abstract
The present invention relates to a pharmaceutical composition for preventing or treating dry eye syndrome and a health functional food composition for preventing or improving dry eye syndrome including α-humulene as an active ingredient, wherein the α-humulene improves the expression level of mucin and recovers the reduced amount of tears in the dry eye-induced eye and thus can effectively prevent, improve or treat dry eye syndrome.
Claims5
A method of increasing expression of mucin in an eye of a subject, comprising:
- providing a pharmaceutical composition comprising α-humulene as an active ingredient;
- and
- administering the pharmaceutical composition to the subject having a non-inflammatory dry corneal epithelial damage,
- wherein the mucin is at least one selected from the group consisting of MUC1, MUC4 and MUC6,
- wherein the α-humulene increases the expression of mucin in the eye so that dry eye syndrome is treated and an amount of tears in the eye is restored.
A method of increasing expression of mucin in an eye of a subject, comprising:
- providing a health functional food composition comprising α-humulene as an active ingredient;
- and
- administering the health functional food to the subject having a non-inflammatory dry corneal epithelial damage,
- wherein the mucin is at least one selected from the group consisting of MUC1, MUC4 and MUC6,
- wherein the α-humulene increases the expression of mucin in the eye so that dry eye syndrome is improved and an amount of tears in the eye is restored.
Dependencies are inferred from the claim text.