Micro-devices for treatment of an eye

A micro-device for corneal cross-linking treatment, comprising:

• a body including an outer portion and an inner portion, the inner portion coupled to the outer portion, the outer portion being disposed about a periphery of the inner portion, the inner portion being shaped such that, when the body is positioned against a surface of an eye, the outer portion contacts the surface of the eye and the inner portion defines a chamber over a cornea of the eye;
• an illumination system including a micro-optical element coupled to the body, the micro-optical element including a plurality of micro-light emitting diodes (micro-LEDs) configured to direct photoactivating light through the inner portion of the body to the cornea of the eye when the body is positioned against the surface of the eye, the photoactivating light generating cross-linking activity with a cross-linking agent applied to the cornea;
• a spatial light modulator including individually addressable pixels configured to block or transmit photoactivating light;
• and
• a controller configured to selectively activate a subset of the micro-LEDs to produce a pattern of the photoactivating light,
• wherein the chamber is configured to receive the cross-linking agent to soak the cornea of the eye.