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US 11,766,202 B2Granted
Filtering in pre-evacuated containers
OwnerJean I Montagu, William Bell +1inventors
InventorsJean I Montagu, William Bell, Sasha Montagu
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OwnerJean I Montagu, William Bell +1inventors
InventorsJean I Montagu, William Bell, Sasha Montagu
Estimating the term…
An independent blood filter device depends on flow geometry to deliver blood serum or plasma free of detrimental levels of hemoglobin. It depends critically on an upstream flow rate or pressure differential limiting control element or device that limits the rate of change of pressure differential across the filter element. Pre-evacuated versions can be used to simultaneously draw blood from a living being and provide pressure differential across the filter element between an evacuated collector and a supply end open to atmosphere. A unit pressurized by hand motion employs the external shape of a partially filled blood collection tube as a piston to produce pressure in advance of the control element or device to create the pressure differential across the filter element to a collector vented to atmosphere. The control element or device is disclosed in numerous forms, including specially sized flow constrictions and compliant arrangements.
A filtering device for filtering blood to obtain serum or plasma in a container, the container having access at both ends and including a blood holding chamber including a spacer ring defining a size of the blood holding chamber, a filter including glass microfibers being located within the container and receiving blood from the blood holding chamber, and a flow rate or pressure differential limiting control element, the limiting element being located upstream, of the filter and designed to limit pressure differential across the filter thereby substantially eliminating homolysis associated with the filter.
A filtering device, comprising
A filtering device, comprising a pre-evacuated container, a filter including microfibers and being located within the container, and a flow rate or pressure differential limiting control element is constructed to limit differential pressure across the filter by restricting flow toward the filter, wherein the limiting element is constructed to passively limit increase in the pressure differential rate of change across the filter to about 10 mmHg thereby substantially eliminating hemolysis associated with the filter.
Dependencies are inferred from the claim text.