US 11,766,184 B2 · Hemodynamic analysis system

Abstract

Articles of manufacture, including an apparatus for detecting a hemodynamic disorder, are provided. A method may include receiving a blood pressure, including an aortic pressure and a distal coronary pressure, over a plurality of heartbeats. The method also includes determining a complement of a ratio of the distal coronary pressure to the aortic pressure for each heartbeat of the plurality of heartbeats. The method also includes determining, based on the complement of the ratio, a maximum complement of the ratio and a minimum complement of the ratio. The method also includes determining, based on the maximum complement and the minimum complement, a pressure-derived coronary flow reserve. The pressure-derived coronary flow reserve includes a ratio of the maximum complement to the minimum complement. The method also includes detecting, based on the pressure-derived coronary flow reserve, a hemodynamic disorder.

Claims18

Dependent claims

A system, comprising:

at least one data processor;
and
at least one memory storing instructions which, when executed by the at least one data processor, result in operations comprising:
receiving, from one or more sensors positioned within a cardiovascular structure of a patient, a blood pressure over a plurality of heartbeats, the blood pressure comprising an aortic pressure and a distal coronary pressure;
determining a complement of a ratio of the distal coronary pressure to the aortic pressure for each heartbeat of the plurality of heartbeats;
determining, based on the complement of the ratio, a maximum complement of the ratio and a minimum complement of the ratio;
determining a pressure-derived coronary flow reserve including a second ratio of the maximum complement to the minimum complement;
detecting, based on the pressure-derived coronary flow reserve and the complement of the ratio of the distal coronary pressure to the aortic pressure, a hemodynamic disorder within the cardiovascular structure of the patient;
and
generating, based on the detection of the hemodynamic disorder, an alert.

7 more elements

A non-transitory computer-readable storage medium including program code, which when executed by at least one data processor, cause operations comprising:

receiving, from one or more sensors positioned within a cardiovascular structure of a patient, a blood pressure over a plurality of heartbeats, the blood pressure comprising an aortic pressure and a distal coronary pressure;
determining a complement of a ratio of the distal coronary pressure to the aortic pressure for each heartbeat of the plurality of heartbeats;
determining, based on the complement of the ratio, a maximum complement of the ratio and a minimum complement of the ratio;
determining a pressure-derived coronary flow reserve including a second ratio of the maximum complement to the minimum complement;
detecting, based on the pressure-derived coronary flow reserve and the complement of the ratio of the distal coronary pressure to the aortic pressure, a hemodynamic disorder within the cardiovascular structure of the patient;
and
generating, based on the detection of the hemodynamic disorder, an alert.

4 more elements

Dependencies are inferred from the claim text.

Hemodynamic analysis system

Life of this patent

Hemodynamic analysis system

Life of this patent

Abstract

Claims18