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US 11,759,478 B2Granted
Non-pyrogenic preparation comprising nanoparticles synthesized by magnetotactic bacteria for medical or cosmetic applications
AssigneeNanobacterie
InventorsEdouard Alphandery, Mickael Durand-Dubief
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Abstract
A non-pyrogenic preparation containing nanoparticles synthesized by magnetotactic bacteria for medical or cosmetic applications. The nanoparticles are constituted by a crystallized mineral central part including predominantly an iron oxide, as well as a surrounding coating without material from the magnetotactic bacteria.
Claims11
A preparation comprising at least one synthetic nanoparticle, the at least one synthetic nanoparticle comprising:
- a crystallized mineral central part comprising predominantly an iron oxide, the central part having been produced by a living organism,
- wherein the central part has at least one property selected in the group consisting of:
- i) the central part is non-pyrogenic,
- and
- ii) the central part comprises less than 50% of organic material;
- wherein the preparation does not comprise non-denatured proteins or is non-immunogenic or wherein the at least one synthetic nanoparticle comprises no non-denatured endotoxins.
3 more elements
A preparation comprising the synthetic nanoparticle obtained by the method comprising the following steps:
- (i) from a preparation of nanoparticles synthesized by a living organism comprising a crystallized central part composed predominantly of an iron oxide and a biological surrounding coating, isolating the central part;
- and
- (ii) optionally sterilizing the preparation, after step (i).
Dependencies are inferred from the claim text.