US 11,759,236 B2Granted

Cartilage repair, preservation and growth by stimulation of bone-chondral interface and delivery system and methods therefor

AssigneeVad Scientific LLC

InventorsVijay Vad, Raghav Barve, Paul Mulhauser, Karl D. Kirk, III

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Abstract

Therapeutics and methods of treatment to repair, preserve and grow cartilage are presented. In addition, systems and methods for delivering a therapeutic to a hard to reach anatomical area, such as, for example, the BCI, are presented. A cannulated delivery device provided with a cutting tip, cutting flutes and threads on its distal end can be provided. Using such an exemplary device, various novel therapies for joint and cartilage repair, preservation and generation can be implemented. The device may have two-needles, with a first cannula/needle, with a finger grip at its distal end, and a longer inner needle to penetrate through the outer needle into the disc, and introduce therapeutics, for example, via a syringe. When provided with a septum at the inner needle's proximal end, the PIARES device is a completely closed system, and its use minimizes trauma.

Claims15

Dependent claims

A method for treating osteoarthritic disorders, said method comprising:

identifying an area of osteoarthritis of articular cartilage in a peripheral joint that comprises a first bone and a second bone;
creating within said first bone a pathway to a bone-cartilage interface associated with said area of osteoarthritis;
and
delivering a bone-cartilage interface therapeutic material, through said pathway, sufficiently close to said bone-cartilage interface so that said method is effective to relieve pain,
wherein said method comprises advancing a delivery device to a location within said first bone such that a distal end of said delivery device is located close to or at said bone-cartilage interface of said articular cartilage in said area of osteoarthritis, and wherein said delivering said bone-cartilage interface therapeutic material comprises delivering said bone-cartilage interface therapeutic material through said delivery device.

2 more elements

Dependencies are inferred from the claim text.

Facts

Application: 17/681,768Filed 26 Feb 2022 · continuation
Priority: 11 Apr 2012
Published: US 2022/0280191 A18 Sep 2022
Granted: 19 Sep 2023
Term ends: Not estimatedThe source records don’t support an estimate.

Classification4 codes

A61B 17/3472
Trocars; Puncturing needles: for bones, e.g. intraosseus injections
A61M 5/158
Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor: needles for infusions; Accessories therefor, e.g. for inserting…
A61B
Medical diagnosis and surgery
A61M
Devices for delivering substances into the body

Family

Application61/686,835Us provisional application · filed 11 Apr 2012
Application61/800,574Us provisional application · filed 15 Mar 2013
Application13/861,360Parent of this continuation · filed 11 Apr 2013
Application15/819,751Parent of this continuation · filed 21 Nov 2017
US 9,827,010 B2Parent of this continuation · filed 28 Nov 2017
Application16/862,448Parent of this continuation · filed 29 Apr 2020
US 2022/0280191 A1Pre-grant publication · published 8 Sep 2022
US 11,389,196 B2Parent of this continuation
US 2014/0088551 A1Published application
US 2018/0317962 A1Published application
US 2020/0253637 A1Published application
US 11,759,236 B2This patent

From the US filing history. Foreign family members aren’t listed.