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US 11,752,243 B2Granted
Blood component sampling cassette, blood sampling circuit set, and blood component sampling system
AssigneeTerumo Kabushiki Kaisha
InventorMasatsugu Igarashi
Life of this patent
Estimating the term…
Abstract
A blood component sampling cassette which can be more efficiently manufactured at lower cost as compared to a typical cassette, a blood sampling circuit set, and a blood component sampling system. A blood component sampling cassette (22) includes a cassette main body (23) made of a soft material to which heat sterilization is applicable. The cassette main body (23) is provided with a retransfusion line (44). The retransfusion line (44) is provided with a reservoir (47) configured to temporarily store a blood component to be returned to a blood donor. The reservoir (47) is pressed by a retransfusion pump (49) to discharge the blood component from the reservoir (47).
Claims20
A biological component sampling cassette, comprising:
- a cassette main body provided with a plurality of flow paths that are blow molded, wherein the cassette main body is configured to be attachable to a separation device that separates a biological component from liquid containing at least one biological component,
- wherein the cassette main body comprises a first sheet of a soft resin to which heat sterilization is applicable and a second sheet of said soft resin, said first and second sheets being bonded to each other to form said plurality of flow paths,
- wherein the plurality of flow paths includes:
- an introduction line configured to introduce the liquid,
- a biological component transfer line configured to transfer, to a sampling container, the biological component obtained by separation processing of the liquid, and
- a return line configured to transfer liquid other than the biological component obtained by separation processing with the separation device,
- wherein the return line is provided with a reservoir configured to temporarily store the liquid to be returned,
- wherein the cassette main body includes a sensor pressing section that presses a reservoir pressure sensor to thereby detect an inner pressure of the reservoir, wherein the sensor pressing section is located in a portion of the return line that is connected between the reservoir and first and second port members of the cassette main body that connect to respective external tubes,
- wherein the first port member and the second port member are at an edge of the cassette main body and adjacent to one another in a first direction that is perpendicular to a second direction,
- wherein the sensor pressing section is between the edge of the cassette main body and the reservoir along the second direction, and
- wherein the reservoir is configured to be expandable and contractable, and is pressed by a return pump provided at the separation device to discharge the liquid from the reservoir.
8 more elements
A biological component sampling circuit set comprising:
- a biological component sampling cassette including a cassette main body provided with a plurality of flow paths that are blow molded, wherein the cassette main body is configured to be attachable to a separation device that separates a biological component from liquid containing at least one biological component;
- a separation processing section connected to the biological component sampling cassette through a first tube and having a processing chamber configured to separate the liquid into multiple biological components by actuation of the separation device;
- and
- a bag connected to the biological component sampling cassette through a second tube,
- wherein the cassette main body comprises a first sheet of a soft resin to which heat sterilization is applicable and a second sheet of said soft resin, said first and second sheets being bonded to each other to form said plurality of flow paths,
- wherein the plurality of flow paths includes:
- an introduction line configured to introduce the liquid;
- a biological component transfer line configured to transfer, to a sampling container, the biological component obtained by separation processing of the liquid;
- and
- a return line configured to transfer liquid other than the biological component obtained by separation processing with the separation device, wherein
- the return line is provided with a reservoir configured to temporarily store the liquid to be returned,
- wherein the cassette main body includes a sensor pressing section that presses a reservoir pressure sensor to thereby detect an inner pressure of the reservoir, wherein the sensor pressing section is located in a portion of the return line that is connected between the reservoir and first and second port members of the cassette main body that connect to respective external tubes,
- wherein the first port member and the second port member are at an edge of the cassette main body and adjacent to one another in a first direction that is perpendicular to a second direction,
- wherein the sensor pressing section is between the edge of the cassette main body and the reservoir along the second direction, and
- wherein the reservoir is configured to selectively expand or contract, and is pressed by a return pump provided at the separation device to discharge the liquid from the reservoir.
12 more elements
A biological component sampling system comprising:
- a separation device configured to separate a biological component from liquid containing at least one biological component;
- and
- a biological component sampling cassette configured to be attachable to the separation device,
- wherein the biological component sampling cassette includes a cassette main body provided with a plurality of flow paths that are blow molded,
- wherein the cassette main body comprises a first sheet of a soft resin to which heat sterilization is applicable and a second sheet of said soft resin, said first and second sheets being bonded to each other to form said plurality of flow paths,
- wherein the plurality of flow paths includes:
- an introduction line configured to introduce the liquid;
- a biological component transfer line configured to transfer, to a sampling container, the biological component obtained by separation processing of the liquid;
- and
- a return line configured to transfer liquid other than the biological component obtained by separation processing with the separation device, wherein
- wherein the return line is provided with a reservoir configured to temporarily store the liquid to be returned,
- wherein the cassette main body includes a sensor pressing section that presses a reservoir pressure detection mechanism to thereby detect an inner pressure of the reservoir, wherein the sensor pressing section is located in a portion of the return line that is connected between the reservoir and first and second port members of the cassette main body that connect to respective external tubes,
- wherein the first port member and the second port member are at an edge of the cassette main body and adjacent to one another in a first direction that is perpendicular to a second direction,
- wherein the sensor pressing section is between the edge of the cassette main body and the reservoir along the second direction, and
- wherein the reservoir is configured to selectively expand or contract, and is pressed by a return pump provided at the separation device to discharge the liquid from the reservoir.
12 more elements
Dependencies are inferred from the claim text.