Compositions and methods for glaucoma
AssigneeCornell University
InventorsJohn T. G. Pena, James Murray Mitchell, Harmon Lawrence Remmel
Life of this patent
Estimating the term…
Abstract
This invention relates to methods and compositions for detecting, identifying and treating glaucoma diseases. More particularly, this invention discloses compositions and methods for affecting intraocular pressure and increasing ocular outflows in glaucoma. Compositions and methods provided include purified and synthesized extracellular vesicle complexes from glaucoma ocular humor for use in methods and devices for detecting, characterizing and treating glaucoma diseases along with active agents. The presence of extracellular vesicle complexes in glaucoma can also be used as a biomarker.
Claims9
A composition, consisting of extracellular vesicle aggregate complexes isolated from a glaucoma ocular humor, wherein the extracellular vesicle aggregate complexes are present in native glaucoma ocular humor, and wherein the extracellular aggregate complexes have at least 10 extracellular vesicles.
Dependencies are inferred from the claim text.