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US 11,752,135 B2Granted
Liquid pharmaceutical formulation
AssigneeProject Pharmaceutics GmbH
InventorsAndreas Schuetz, Klaus Hellerbrand
Life of this patent
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Abstract
The present invention relates to a liquid pharmaceutical formulation, which is stable at room temperature, being essentially free of water, comprising a) at least one easily degradable active pharmaceutical ingredient, b) at least one pharmaceutically acceptable organic solvent and c) at least one pharmaceutically acceptable alkaline earth metal salt and its use in medicine.
Claims16
A liquid pharmaceutical formulation, having a water content of below 1.0% (w/w) water, comprising
- a) Bendamustine as an active pharmaceutical ingredient;
- b) at least one pharmaceutically acceptable organic solvent comprising propylene glycol, polyethylene glycol 400 (PEG 400) or a mixture of propylene glycol and PEG 400;
- and
- c) a calcium salt.
1 more element
Dependencies are inferred from the claim text.