Polycaprolactone-based fibers and implants including same
AssigneeCook Biotech Incorporated
InventorsBhavin Shah, Benjamin Kline, Rhonda Peck
Life of this patent
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Abstract
A polymeric material fiber includes a polymeric material which is a homopolymer of caprolactone or a copolymer of at least 90% by weight of caprolactone and one or more additional monomers. An implantable mesh includes this fiber alone or combined with one or more additional fiber materials. Methods for treating patients involve implanting the fiber material, for example incorporated in a mesh.
Claims32
A melt extruded, oriented polymeric material fiber, wherein the polymeric material is a homopolymer of caprolactone or a copolymer of at least 90% by weight of caprolactone and one or more additional monomers;
- and further wherein:
- (i) the polymeric material fiber has a tensile strength of about 450 MPa to about 650 MPa;
- and/or
- (ii) the polymeric material fiber has an elongation at break in the range of 45% to 65%;
- and/or
- (iii) the polymeric material fiber has an elastic modulus in the range of 750 MPa to 1200 MPa;
- and/or
- (iv) the tensile strength of the polymeric material fiber, as measured after immersion in phosphate buffered physiological saline for 60 minutes, decreases less than 20% after immersion in phosphate buffered physiological saline for 6 months.
A method for making a melt extruded, oriented polymeric material fiber, comprising:
- melt extruding a polymeric material which is a homopolymer of caprolactone or a copolymer of at least 90% by weight of caprolactone and one or more additional monomers, to form an extrudate;
- solidifying the extrudate by cooling the polymeric material;
- and
- drawing the extrudate so as to stretch harden the polymeric material
- wherein the polymeric material fiber has a tensile strength of about 450 MPa to about 650 MPa, and/or wherein the polymeric material fiber has an elongation at break in the range of 45% to 65%, and/or wherein the polymeric material fiber has an elastic modulus in the range of 750 MPa to 1200 MPa, and/or wherein the tensile strength of the polymeric material fiber, as measured after immersion in phosphate buffered physiological saline for 60 minutes, decreases less than 20% after immersion in phosphate buffered physiological saline for 6 months.
An implantable medical mesh product, comprising:
- a mesh structure comprised of woven and/or knit fibers, wherein the fibers include at least one melt extruded, oriented polymeric material fiber, wherein the polymeric material is a homopolymer of caprolactone or a copolymer of at least 90% by weight of caprolactone and one or more additional monomers;
- and
- wherein the polymeric material fiber has a tensile strength of about 450 MPa to about 650 MPa, and/or wherein the polymeric material fiber has an elongation at break in the range of 45% to 65%, and/or wherein the polymeric material fiber has an elastic modulus in the range of 750 MPa to 1200 MPa, and/or wherein the tensile strength of the polymeric material fiber, as measured after immersion in phosphate buffered physiological saline for 60 minutes, decreases less than 20% after immersion in phosphate buffered physiological saline for 6 months.
Dependencies are inferred from the claim text.