Radiopaque polymers
AssigneeBiocompatibles UK Limited
InventorsKoorosh Ashrafi, Hugh Britton, Francesco Cuda, Andrew Lennard Lewis, Cristian Parisi, Yiqing Tang, Sean Leo Willis
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AssigneeBiocompatibles UK Limited
InventorsKoorosh Ashrafi, Hugh Britton, Francesco Cuda, Andrew Lennard Lewis, Cristian Parisi, Yiqing Tang, Sean Leo Willis
Estimating the term…
The present disclosure relates to radiopaque PVA polymers where the PVA has a first pendant group and a second pendant group, wherein the first pendant group comprises a first phenyl group bearing 1 to 5 iodine atoms, and the second pendant group comprises either (a) a second phenyl group bearing 1 to 3 substituents selected from the group W and optionally 1 to 4 iodine substituents, the group(s) W and the optional iodines being the sole substituents of the second phenyl group. Each W is selected from —OH, —COOH, —SO3H, —OPO3H2, —O—(C1-4alkyl), —O—(C1-4alkyl)OH, —O—(C1-4alkyl)R2, —O—(C2H5O)qR1—(C═O)—O—C1-4alkyl and —O—(C═O)C1-4alkyl; wherein R1 is H or C1-4 alkyl; R2 is —COOH, —SO3H, or —OPO3H2; q is an integer from 1 to 4; wherein the group W may be in the form of a pharmaceutically acceptable salt; or (b) a pyridyl group; which is optionally in the form of a pyridinium ion.
A polymer comprising polyvinyl alcohol (PVA), the PVA having a first pendant group and a second pendant group, wherein the first pendant group comprises a first phenyl group bearing 1 to 5 iodines as the sole substituent(s) of the first phenyl group, and wherein the second pendant group comprises a second phenyl group bearing 1 to 3 substituents selected from the group W and optionally 1 to 4 iodine substituents, the group(s) W and the optional iodines being the sole substituents of the second phenyl group;
Dependencies are inferred from the claim text.