US 11,744,250 B2 · Insect inhibitory proteins

Abstract

Pesticidal proteins exhibiting inhibitory, suppressive, and toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC4064 and TIC4064 amino acid sequence variants. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC4064 and TIC4064 amino acid sequence variant pesticidal proteins are also provided.

Claims18

Dependent claims

A recombinant nucleic acid molecule comprising a heterologous promoter operably linked to a polynucleotide segment encoding a pesticidal protein, wherein:

a. said pesticidal protein comprises the amino acid sequence as set forth in SEQ ID NO:8;
or
b. said polynucleotide segment comprises the nucleotide sequence as set forth in SEQ ID NO:7.

Dependencies are inferred from the claim text.

Facts

Application

17/559,857Filed 22 Dec 2021 · us provisional application

Priority

23 Dec 2020

Published

US 2022/0192200 A123 Jun 2022

Granted

5 Sep 2023

Term ends

Not estimatedThe source records don’t support an estimate.

Classification17 codes

A01N 63/50
Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances…:…
A01P 7/04
Arthropodicides: insecticides
C07K 14/32
From bacteria: from Bacillus
C07K 14/325
From Bacillus: bacillus thuringiensis crystal peptides, i.e. delta-endotoxins

Insect inhibitory proteins

Life of this patent

Insect inhibitory proteins

Life of this patent

Abstract

Claims18