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US 11,739,217 B2Granted
Engineered skin equivalent, method of manufacture thereof and products derived therefrom
AssigneesVitroLabs Inc, King's College London
InventorsIngvar Helgason, Dusko Ilic
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Abstract
Disclosed herein are synthetic leathers, artificial epidermal layers, artificial dermal layers, layered structures, products produced therefrom and methods of producing the same.
Claims18
A method of forming a tanned synthetic leather, wherein the method comprises:
- a) forming an artificial dermal layer comprising a fibroblast on a scaffold, wherein the scaffold comprises cellulose or a modified version thereof;
- b) processing the artificial dermal layer to provide an extracellular matrix;
- and
- c) tanning at least a portion of the extracellular matrix to generate the tanned synthetic leather.
1 more element
A method of forming a tanned synthetic leather, wherein the method comprises:
- a) forming a cell layer comprising a fibroblast on a scaffold, wherein the scaffold comprises cellulose or a modified version thereof;
- b) wherein the cell layer comprises collagen;
- and
- c) tanning at least a portion of the collagen to generate the tanned synthetic leather.
1 more element
Dependencies are inferred from the claim text.