2,3-dihydro-1h-imidazo{1,2-a}pyrimidin-5-one and this 1,2,3,4-tetrahydropyrimido{1,2-a}pyrimidin-6-one derivatives comprising a substituted morpholine, preparation thereof and pharmaceutical use thereof

A compound of formula (I):

• in which:
• p is an integer 0, and q is an integer 2;
• R1 is a —(CH2)m—Ra radical with m being the integer 1 and Ra an optionally substituted monocyclic heteroaryl radical;
• R2 and R3, which may be identical or different, are chosen from a hydrogen atom and an alkyl radical optionally substituted with one or more fluorine atoms, it being understood that R2 and R3 are not both CF3 and R2 and R3 are not both hydrogen;
• R4 is a hydrogen atom, a fluorine or chlorine atom, a methyl radical or a CN radical;
• and
• the morpholine residue is substituted with the radicals R5 to R12, which may be identical or different, chosen from a hydrogen atom and methyl and ethyl radicals optionally substituted with a fluorine atom or a hydroxyl radical, it being understood that at least one of R5 to R12 is not a hydrogen atom,
• the heteroaryl radicals that Ra represents being, in addition, optionally substituted with one or more alkyl radicals themselves optionally substituted with one or more radicals, which may be identical or different, chosen from fluorine atoms and hydroxyl and alkoxy radicals;
• all the alkyl, alkylene and alkoxy radicals above being linear or branched and containing at most 7 carbon atoms,
• it being understood that one or more of the hydrogen atoms of said products of formula (I) can be a deuterium atom;
• said products of formula (I) being in any of the possible racemic, enantiomeric and diastereoisomeric isomer forms, and also the addition salts with inorganic and organic acids or with inorganic and organic bases of said products of formula (I).