Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals
AssigneeThe Government of the United States of America, as represented by the Secretary of the Navy
InventorsR. Andrew McGill, Courtney A. Roberts
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Abstract
The invention relates to strong hydrogen-bond acidic sorbents. The sorbents may be provided in a form that limits or eliminates intramolecular bonding of the hydrogen-bond acidic site between neighboring sorbent molecules, for example, by providing steric groups adjacent to the hydrogen-bond acidic site. The hydrogen bond site may be a phenolic structure based on a bisphenol architecture. The sorbents of the invention may be used in methods for trapping or detecting hazardous chemicals or explosives.
Claims1
A method for separating a hydrogen-bond basic analyte from a mixture, the method comprising:
- coating a bisphenol sorbent comprising a compound of formula I or formula II as a chromatographic stationary phase,
- wherein
- R1 is selected from the group consisting of prop-1-en-2-yl;
- -dimethyl(phenyl)silyl;
- trimethylsilyl;
- diphenylmethyl;
- methylthio;
- prop-2-enyl;
- benzyl;
- ethylthio;
- cyclopropyl;
- 2-(trimethylsilyl)ethyl;
- 2,2-dimethylpropyl;
- 2-methylpropyl;
- phenylethyl;
- propyl;
- butyl;
- sec-butyl;
- pentyl;
- heptyl;
- propan-2-yl;
- cyclopentyl;
- cyclohexyl;
- cyclobutyl;
- 3-ethylpentan-3-yl;
- ethyl;
- 1,1-dimethylpropyl;
- (trimethylsilyl)methyl;
- trifluoromethyl;
- and fluoro;
- and
- R2 is selected from the group consisting of, methyl;
- tert-butyl;
- prop-1-en-2-yl;
- dimethyl(phenyl)silyl;
- trimethylsilyl;
- diphenylmethyl;
- methylthio;
- prop-2-enyl;
- benzyl;
- ethylthio;
- cyclopropyl;
- 2-(trimethylsilyl)ethyl;
- 2,2-dimethylpropyl;
- 2-methylpropyl;
- phenylethyl;
- propyl;
- butyl;
- sec-butyl;
- pentyl;
- heptyl;
- propan-2-yl;
- cyclopentyl;
- cyclobutyl;
- 3-ethylpentan-3-yl;
- ethyl;
- 1,1-dimethylpropyl;
- (trimethylsilyl)methyl;
- trifluoromethyl;
- and fluoro;
- and
- contacting the chromatographic stationary phase coated with bisphenol sorbent with a sample comprising a hydrogen-bond basic analyte, wherein the bisphenol sorbent selectively binds with hydrogen-bond basic analytes having higher hydrogen-bond basicity over other chemicals having lower hydrogen-bond basicity, resulting in separation of the analyte from other components in the sample.
Dependencies are inferred from the claim text.