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US 11,732,084 B2Granted
Anti-microbial hydrogel
AssigneeUniversiteit Gent
InventorsArn Mignon, Tom Gheysens, Sandra Van Vlierberghe, Peter Dubruel
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Abstract
Hydrogels are provided that include an antimicrobial agent and a cross-linkable urethane-based polymer (CUP). Such hydrogels may be used for the controlled-release of antimicrobial agents as well as in the manufacturing of wound dressings. Wound dressings are provided that comprise a hydrogel as defined herein.
Claims15
A hydrogel comprising:
- an antimicrobial agent;
- and
- a cross-linkable urethane-based polymer represented by formula (I):
- where:
- each occurrence of X and Y is independently a moiety comprising one or more group chosen from acrylate groups, (multi)methacrylate groups, (multi)acrylate group, thiolactones, or thiol-ene crosslinkable groups;
- each occurrence of Spacer is independently selected from the group consisting of oligo(ethylene oxide), oligo(propylene oxide), oligo(caprolactone), oligo(lactide), and oligo(glycolide);
- m and n are each independently from 1 to 6;
- p is from 1 to 10;
- and
- each occurrence of Backbone is independently selected from the group consisting of polyethylene glycol), poly(vinyl pyrrolidone), poly(N-vinyl caprolactam), and combinations thereof.
7 more elements
Dependencies are inferred from the claim text.