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US 11,730,803 B2Granted
Cancer immunotherapy using virus particles
AssigneesCase Western Reserve University, Trustees of Dartmouth College
InventorsNicole F. Steinmetz, Amy M. Wen, Steven Fiering, Patrick H. Lizotte
Life of this patent
Estimating the term…
Abstract
A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.
Claims15
A composition for delivering an active pharmaceutical ingredient directly to a cancer in a subject in need thereof, wherein said composition comprises a pharmaceutically acceptable carrier and therapeutically effective amounts of:
- the active pharmaceutical ingredient, wherein the active pharmaceutical ingredient is an in situ vaccine that comprises at least one of cowpea mosaic virus or cowpea mosaic virus-like particles, wherein the cowpea mosaic virus and cowpea mosaic virus-like particles are not used as a vehicle for drug or antigen delivery;
- and
- an anticancer agent.
A unit dosage form of a formulation of an in situ vaccine and an anticancer agent;
- wherein the in situ vaccine comprises at least one of cowpea mosaic virus or cowpea mosaic virus-like particles, wherein the cowpea mosaic virus and cowpea mosaic virus-like particles are not used as a vehicle for drug or antigen delivery.
Dependencies are inferred from the claim text.