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US 11,726,012 B2Granted
Composition for biotissue clearing and biotissue clearing method using same
AssigneeBinaree, INC.
InventorSun Hyun Park
Life of this patent
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Abstract
The present invention relates to a composition for clearing a biotissue and a method for clearing a biotissue using thereof.
Claims5
A method for clearing a biotissue, the method comprising a step of clearing a fixed biotissue by contacting the fixed biotissue with a composition comprising an amino acid represented by Formula 1, or a salt thereof:
- wherein R1 is CH3,
- wherein R2 is a straight-chained or branched C8-C20 alkylcarbonyl, and
- wherein R3 is H;
- and
- wherein the composition further comprises one or more selected from the group consisting of urea, 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate) (CHAPS), 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate) (CHAPSO), sucrose, fructose, glycerol, diatrizoic acid, t-octylphenoxypolyethoxyethanol, polyoxyethylene (20) sorbitan monolaurate, 2-2-thiodiethanol, and iohexol.
2 more elements
Dependencies are inferred from the claim text.