Production of 2-keto-3-deoxy-d-gluconic acid in filamentous fungi
AssigneeBP Corporation North America Inc.
InventorsMolly Krebs, Chris Phillips, Fernando Valle
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Abstract
A recombinant filamentous fungi that includes reduced 2-Keto-3-Deoxy-Gluconate (KDG) aldolase enzyme activity as compared to the filamentous fungi not transformed to have reduced KDG aldolase enzyme activity is provided. Also provided is a method of producing KDG.
Claims15
A genetically modified filamentous fungus having reduced 2-Keto-3-Deoxy-Gluconate (KDG) aldolase enzyme activity as compared to the KDG aldolase enzyme activity in a wild type counterpart of said filamentous fungus, wherein said filamentous fungus is an Aspergillus niger strain.
The filamentous fungus claim of 1, wherein the Aspergillus niger strain is selected from the group consisting of NRRL 322, NRRL 328, NRRL 566, NRRL 599 and NRRL 2270.
Dependencies are inferred from the claim text.