# US 11,707,568 B2 · Method and system for providing a therapeutic agent to an implanted infusion device

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- Number: US 11,707,568 B2
- Document ID: US11707568B2
- Status: Granted
- Kind: B2
- Application number: 16/799,864
- Filed: 2020-02-25
- Published: 2020-08-27
- Granted: 2023-07-25
- Earliest claimed: 2019-02-27
- Assignees: B. Braun Miethke GmbH & Co. KG
- Applicants: B. Braun Miethke GmbH & Co. KG
- Inventors: Brandon Loudermilk; Michael Sörensen
- Web page: https://patentgrep.com/patent/US11707568B2

## CPC

- A61M 5/14276: {specially adapted for implantation}
- A61M 5/1582: {Multi-lumen needles}
- A61M 5/162: Needle sets, i.e. connections by puncture between reservoir and tube
- A61M 5/16809: {by repeated filling and emptying of an intermediate volume}
- A61M 5/329: {characterised by features of the needle shaft}
- A61M 5/3291: {Shafts with additional lateral openings}
- A61M 39/0208: {Subcutaneous access sites (implantable infusion devices A61M5/14276; transcutaneous access sites A61M39/0247)}
- A61M 2005/1588: {having means for monitoring, controlling or visual inspection, e.g. for patency check or for avoiding extravasation}
- A61M 2039/0217: {at least some chambers being stacked separated by another septum}
- A61M 2039/0244: {having means for detecting an inserted needle}
- A61M 2205/0244: Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
- A61M 2205/14: Detection of the presence or absence of a tube, a connector or a container in an apparatus
- A61M 2205/3317: Electromagnetic, inductive or dielectric measuring means
- A61M 2205/3523: using telemetric means
- A61M 2205/50: with microprocessors or computers
- A61M 2205/502: User interfaces, e.g. screens or keyboards
- A61M 2205/52: with memories providing a history of measured variating parameters of apparatus or patient
- A61M 2205/582: by tactile feedback
- A61M 2209/045: for filling, e.g. for filling reservoirs
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

A system for refilling a multi-chamber implantable infusion device is presented. The infusion device has a refill chamber which is accessible through an external septum of a refill port. The refill chamber is divided by an inner septum into an upper reservoir and a lower reservoir. The lower refill chamber is refilled with lower reservoir needles having a needle opening axially placed to align with the lower reservoir. The upper reservoir is refilled with an upper reservoir needle having an opening aligned with the upper reservoir. Magnetic portions are provided in the needles to localize and identify the needle. A processor within the infusion device is connected to magnetic field sensors which sense magnetic portions of the needle and recognize information encoded magnetically within the needle.

## Claims

### Claim 1

An implantable infusion device, comprising:
a housing;
a refill chamber arranged within the housing, the refill chamber being accessible through a refill port; a self-sealing external septum disposed at the refill port which forms an access opening of an upper chamber in the refill chamber;
a self-sealing inner septum disposed within the refill chamber below the external septum which separates the upper chamber from a lower chamber;
a magnetic field sensor arranged proximal to the refill chamber; and
a processor operatively connected to the magnetic field sensor,
wherein one needle for refilling at least one of the upper chamber and the lower chamber can be inserted in the refill port, wherein the one needle is selected from a plurality of needles comprising
a first needle for refilling the upper chamber, the first needle having an upper opening positioned for refilling the upper chamber when the first needle is inserted in the refill port and the first needle having a first magnetic portion with an associated first magnetic field, the first magnetic field having a first orientation and a first intensity, and
a second needle for refilling the lower chamber, the second needle having a lower opening positioned for refilling the lower chamber when the second needle is inserted in the refill port and the second needle having a second magnetic portion with an associated second magnetic field, the second magnetic field having a second orientation and a second intensity, and
wherein the first orientation and/or the first intensity of the first magnetic field within the first magnetic portion differs from the second orientation and/or the second intensity of the second magnetic field within the second magnetic portion,
wherein the processor is configured, in response to a signal received from the magnetic field sensor, to detect a presence of a-the one needle in the refill chamber and to associate, by evaluating at least one of an orientation and an intensity of a sensed magnetic field at the magnetic field sensor, the sensed magnetic field with the first needle for refilling the upper chamber and a position of a needle opening of the one needle in the refill chamber with the upper chamber, or with the second needle for refilling the lower chamber and the position of the needle opening of the one needle in the refill chamber with the lower chamber.

### Claim 2 (depends on 1)

The implantable infusion device as in claim 1,
further comprising a contact sensor arranged at a bottom of the refill chamber,
wherein the magnetic field sensor is a Hall effect sensor arranged within the housing adjacent to the refill chamber, and
wherein the processor is configured, in response to signals received from the magnetic field sensor and from the contact sensor, to detect the presence of the one needle in the refill chamber and to associate the position of the needle opening of the one needle in the refill chamber with the lower chamber or the upper chamber.

### Claim 3 (depends on 1)

The implantable infusion device as in claim 1,
wherein the magnetic field sensor is a first Hall effect sensor arranged within the housing adjacent to the refill chamber,
wherein the device further comprises a second Hall effect sensor arranged within the housing adjacent to the refill chamber,
wherein the processor is configured, in response to signals received from the first Hall effect sensor and from the second Hall effect sensor, to detect the presence of the one needle in the refill chamber and to associate the position of the needle opening of the one needle in the refill chamber with the lower chamber or the upper chamber.

### Claim 4 (depends on 1)

The implantable infusion device as in claim 1,
further comprising a wireless transmitter operatively connected to the processor,
wherein the processor is configured to transmit a signal relating to the association of the position of the needle opening of the one needle with the lower chamber or the upper chamber to an external device.