Microdialysis device comprising attachment sheet
AssigneeSenzime AB (Publ.)
InventorsPernilla Abrahamsson, Robert Herz, Einar Pontén, Bjoern Glaesel
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to a dialysis device (1), more particularly a microdialysis device for the sampling of substances from the surface of a body organ. The device is particularly useful in the context of the monitoring of a moving organ, such as a beating heart, as the device comprises attachment means (2) allowing for a flexible and reliable attachment thereto. Furthermore, the microdialysis device provides for an efficient exchange of substances, such as metabolic substances, between the organ and the dialysis fluid through a semi-permeable material forming part of the device. There is also provided a method encompassing the device of the disclosure.
Claims16
An elongated microdialysis device (1) comprising a distal part (2) and a proximal part (3), said proximal part (3) comprising an inlet (4) and an outlet (5), said inlet (4) and outlet (5) adapted to allow a fluid to flow through said microdialysis device (1) from said inlet (4) through said proximal part (3) via said distal part (2) and back to said outlet (5), along substantially an entire length of said microdialysis device (1),
- wherein said distal part (2) of said microdialysis device (1) is configured for temporary attachment and/or placement on a surface of a human or animal organ, and said distal part (2) comprises a probe (2) for sampling substances present on said surface of said organ and indicating a condition of said organ, said probe comprising
- an inlet channel (10) adapted to receive fluid originating from said inlet (4),
- an outlet channel (11) adapted to receive fluid originating from said inlet channel (10),
- wherein at least part of an outer surface (12) of said probe (2) is adapted to be placed on said surface of an organ, said part of the outer surface of said probe comprising a semi-permeable material (13, 23) adapted to allow passage of substances from the outside of said probe through said semi-permeable material (13, 23) into said fluid within said microdialysis device (1), characterized in that said device further comprises an attachment sheet (14), said attachment sheet (14) being configured to facilitate placement and/or attachment of said probe (2) to said organ surface, the side of the probe (2) comprising the semi-permeable material (13) being adapted to lie against said organ surface,
- wherein said attachment sheet is adapted to be arranged essentially flat against the organ surface when said distal part (2) is arranged on a surface of a human or animal organ, said attachment sheet (14) comprising an opening essentially corresponding to said part of the outer surface comprising the semi-permeable material (13, 23), and
- wherein said attachment sheet is made of a substantially fluid-tight material and blocks access to said semi-permeable material by surrounding fluids when the probe is attached to a surface by the attachment sheet.
Dependencies are inferred from the claim text.