Hydrogels from dynamic covalent networks
AssigneeInternational Business Machines Corporation
InventorsDylan J. Boday, Mareva B. Fevre, Jeannette M. Garcia, James L. Hedrick, Rudy J. Wojtecki
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Abstract
In an embodiment is provided a polymer that includes a plurality of N-J-N or N—C—S repeating units, wherein each J is independently a carbon atom, an alkyl group, or an aryl group; a plurality of hydrophilic groups bonded with the repeating units; and a plurality of hydrophobic groups bonded with the hydrophilic groups and the repeating units. In another embodiment is provided hydrogels of such polymers. The hydrogels may be used as delivery vehicles for various payloads. In another embodiment is provided methods of forming such polymers.
Claims20
A method of forming a polymer, the method comprising:
- reacting a hydrophobic component with a hydrophilic component to form a polymer having hydrophobic sections and hydrophilic sections, the polymer having a general structure selected from the group consisting of
- wherein:
- each instance of R1 is independently aryl, polyester, or polyamide;
- each instance of R6 is independently a group having hydrophilic components;
- each instance of R2 and R5 is independently an organic or hetero-organic group;
- each instance of R3 is independently an electron-deficient organic or hetero-organic group;
- each instance of R7 is a trivalent organic or hetero-organic group;
- each instance of X is independently a hydrophobic group;
- each instance of n is a positive integer;
- and
- wavy bonds in a structure signify covalent bonds to other atoms.
A method of forming a polymer, the method comprising:
- reacting a hydrophobic component with a hydrophilic component to form a polymer having hydrophobic sections and hydrophilic sections, the polymer having a general structure selected from the group consisting of
- wherein:
- each instance of R1 is independently aryl, polyester, or polyamide;
- each instance of R6 is independently a group having hydrophilic components;
- each instance of R2 and R5 is independently an organic or hetero-organic group;
- each instance of R3 is independently an electron-deficient organic or hetero-organic group;
- each instance of R7 is a trivalent organic or hetero-organic group;
- each instance of X is independently a hydrophobic group;
- each instance of n is a positive integer;
- wavy bonds in a structure signify covalent bonds to other atoms;
- and
- wherein:
- the hydrophobic component is selected from the group consisting of
- wherein:
- G is any carbon-bondable substituent;
- and
- each instance of n is a positive integer.
A method of forming a polymer, the method comprising:
- reacting a hydrophobic component with a hydrophilic component to form a polymer having hydrophobic sections and hydrophilic sections, the polymer having a general structure selected from the group consisting of
- wherein:
- each instance of le is independently aryl or polyester;
- each instance of R6 is independently a group having hydrophilic components;
- each instance of le and R5 is independently an organic or hetero-organic group;
- each instance of R3 is independently an electron-deficient organic or hetero-organic group;
- each instance of R7 is a trivalent organic or hetero-organic group;
- each instance of X is independently a hydrophobic group;
- each instance of n is a positive integer;
- and
- wavy bonds in a structure signify covalent bonds to other atoms.
Dependencies are inferred from the claim text.