Back to results
US 11,702,383 B2Granted
Methods for producing D-α-methyldopa
AssigneeImmunoMolecular Therapeutics, Inc.
InventorsXing Fu, Rajesh Shukla
Life of this patent
Estimating the term…
Abstract
The present invention provides methods of synthesizing D-α-methyldopa and L-α-methyldopa.
Claims20
A method of producing D-α-methyldopa, comprising the steps of:
- (1-a) reacting compound 1,
- with L-tartaric acid, thereby producing compound 2,
- (1-b) reacting compound 2 with aqueous HCl, thereby producing compound 3,
- (1-c) reacting compound 3 with hydrochloric acid, thereby producing compound 4,
- and
- (1-d) reacting compound 4 with hydrobromic acid in the presence of an antioxidant to produce D-α-methyldopa.
3 more elements
A method of producing D-α-methyldopa, comprising the steps of:
- (1-a) reacting compound 1,
- with L-tartaric acid, thereby producing compound 2,
- (2-b) reacting compound 2 with a chlorinating agent to produce compound 3,
- and
- (2-c) reacting compound 3 with hydrobromic acid in the presence of an antioxidant, thereby producing D-α-methyldopa.
2 more elements
A method of producing D-α-methyldopa, comprising the steps of:
- (1-a) reacting compound 1,
- with L-tartaric acid, thereby producing compound 2,
- (1-b) reacting compound 2 with aqueous HCl, thereby producing compound 3,
- and
- (2-c) reacting compound 3 with hydrobromic acid in the presence of antioxidant thereby producing D-α-methyldopa.
2 more elements
Dependencies are inferred from the claim text.