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US 11,701,654 B2Granted
Fluid connector
AssigneeCellares Corporation
InventorsVladimir Azersky, Fabian Gerlinghaus, Daniele Malleo, Brian Alexander Pesch, Bharat S. Thakkar, Wilson Wai Toy
Life of this patent
Estimating the term…
Abstract
Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.
Claims29
A system for processing cell products in parallel comprising:
- a sterile enclosure;
- at least one robotic arm positioned within the sterile enclosure, the at least one robotic arm attached to a linear rail;
- a first cartridge including a port and a liquid transfer bus, wherein the first cartridge is capable of receiving a cell product to be processed and of interfacing with one or more instruments;
- a first instrument including a first slot positioned within the sterile enclosure, the first instrument comprising a sterile liquid transfer instrument configured to transfer fluid in and out of the first cartridge via the port;
- and
- a second instrument including a second slot positioned within the sterile enclosure, the second instrument comprising a bioreactor instrument configured to enable expansion of cells within the first cartridge,
- wherein the at least one robotic arm is configured to move the first cartridge between the first slot within the first instrument and the second slot within the second instrument in order to process a cell product within the first cartridge.
4 more elements
A system for processing cell products in parallel comprising:
- a sterile enclosure;
- a pair of robotic arms positioned within the sterile enclosure, each of the robotic arms independently configured for moving one or more cartridges;
- a first cartridge including a port a liquid transfer bus, wherein the first cartridge is capable of receiving a cell product to be processed and of interfacing with one or more instruments;
- a first instrument including a first slot positioned within the sterile enclosure, the first instrument comprising a sterile liquid transfer instrument configured to transfer fluid in and out of the port of the first cartridge;
- and
- a second instrument including a second slot positioned within the sterile enclosure, the second instrument comprising a bioreactor instrument configured to enable cell expansion within the first cartridge,
- wherein at least one of the pair of robotic arms is configured to move the first cartridge from the feedthrough to either of the first slot within the first instrument or the second slot within the second instrument in order to process the cell product within the first cartridge.
4 more elements
A system for processing cell products in parallel comprising:
- a sterile enclosure including an air filtration inlet and a feedthrough;
- at least one robotic arm positioned within the sterile enclosure, the at least one robotic arm attached to a linear rail;
- a first cartridge including a port and two or more modules fluidically coupled by a liquid transfer bus, wherein each of the modules is capable of receiving a cell product to be processed, and wherein each of the modules is capable of interfacing with one or more instruments;
- a first instrument including a first slot positioned within the sterile enclosure, the first instrument comprising a sterile liquid transfer instrument configured to transfer fluid in and out of the port of the first cartridge;
- and
- a second instrument including a second slot positioned within the sterile enclosure, the second instrument comprising a bioreactor instrument configured to enable cell expansion within the first cartridge,
- wherein the at least one robotic arm is configured to move the first cartridge from the feedthrough to either of the first slot within the first instrument or the second slot within the second instrument in order to process a cell product within the first cartridge.
4 more elements
A system for processing cell products in parallel comprising:
- a sterile enclosure including an air filtration inlet for maintaining an ISO8 environment or better and a feedthrough;
- a pair of robotic arms positioned within the sterile enclosure, each of the robotic arms independently configured for moving one or more cartridges;
- a first cartridge including a port and two or more modules fluidically coupled by a liquid transfer bus, wherein each of the modules is capable of receiving a cell product to be processed, and wherein each of the modules is capable of interfacing with one or more instruments;
- a first instrument including a first slot positioned within the sterile enclosure, the first instrument comprising a sterile liquid transfer instrument configured to transfer fluid in and out of the port of the first cartridge;
- and
- a second instrument including a second slot positioned within the sterile enclosure, the second instrument comprising a bioreactor instrument configured to enable cell expansion within the first cartridge,
- wherein at least one of the pair of robotic arms is configured to move the first cartridge from the feedthrough to either of the first slot within the first instrument or the second slot within the second instrument in order to process a cell product within the first cartridge.
4 more elements
Dependencies are inferred from the claim text.