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US 11,701,452 B2Granted
Synthetic hydrogel composite
AssigneeDuke University
InventorsBenjamin J. Wiley, Huayu Tong, Jiacheng Zhao
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Abstract
Cellulose-reinforced hydrogels may include a cellulose nanofiber network and an interstitial hydrogel portion within interstitial regions of the cellulose nanofiber network, the interstitial hydrogel portion comprising polyvinyl alcohol (PVA), wherein the hydrogel component has a crystallinity of 20% or greater.
Claims10
A method of forming an implant having a cellulose-reinforced hydrogel, comprising:
- attaching a cross-linked cellulose nanofiber network to a top bearing surface of the implant;
- infiltrating a hydrogel component within interstitial regions of the cross-linked cellulose nanofiber network to form the cellulose-reinforced hydrogel;
- and
- annealing the cellulose-reinforced hydrogel so that a crystalline content of the hydrogel component has a crystallinity of 20% or greater,
- wherein the cellulose-reinforced hydrogel comprises at least 20% by weight of water,
- wherein the cellulose-reinforced hydrogel has a tensile strength exceeding 40 MPa.
3 more elements
Dependencies are inferred from the claim text.