Use of gTso thal in manufacturing medicament for promotion of MS-275 to cross blood-brain barrier
AssigneeNorthwest Institute of Plateau Biology, Chinese Academy of Sciences
InventorsXiaohui Zhao, Ting Zhang, Huilan Yue, Jihong Tao, Wenjing Jia, Guoying Zhou, Lixin Wei, Chen Chen
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Abstract
The present invention relates to use of gTso thal in manufacturing a medicament for the promotion of MS-275 to cross the blood-brain barrier (BBB), and belongs to the technical field of pharmaceutical preparation. Administration of the medicament manufactured by the use of the present invention in combination with MS-275 significantly increases MS-275 to cross the BBB into the brain tissue, and prominently promotes the accumulation of MS-275 therein.
Claims12
A medicament for the promotion of MS-275 to cross the blood-brain barrier (BBB), comprising gTso thal and pharmaceutically acceptable excipients.
A method for manufacturing a medicament for the promotion of MS-275 to cross the BBB by gTso thal, comprising the following steps:
- mixing gTso thal with pharmaceutically acceptable excipient(s) to manufacture the medicament.
A method for promoting MS-275 to cross by the blood-brain barrier (BBB) of a patient in need of MS-275 treatment, comprising administering a medicament comprising gTso thal and one or more pharmaceutically acceptable excipients, in combination with MS-275.
Dependencies are inferred from the claim text.