US 11,699,524 B2Granted

System for continuous detection and monitoring of symptoms of Parkinson's disease

AssigneeVerily Life Sciences LLC

InventorsMark Murphy, Erin Soderberg

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Abstract

A system is provided to monitor, over time, one or more physical variables related to a severity or progression of a movement disorder and/or of symptoms thereof. The monitored physical variables can include speech sounds; keyboard outputs; or accelerations, rotations, or other properties of the motion of one or more body parts. The system operates to detect, based on the monitored one or more physical variables, potential changes in the degree and/or character of the movement disorder symptoms. In response to detecting such a potential change, the system provides the user with one or more tasks that the user can perform. The system detects one or more properties of the user's performance and, based on that detection, determines the severity or progression of the movement disorder. The tasks can include stepping, turning, standing, sitting, reaching, typing, pointing, manipulating an object, speaking into a microphone, or other tasks.

Claims20

Dependent claims

A body-mountable device that is mountable to a body segment of a person and that comprises:

a first sensor configured to monitor motion of the body segment of the person when the body-mountable device is mounted to the body segment of the person;
a second sensor configured to monitor performance of a motor task;
a user interface;
and
a controller communicatively coupled to the first sensor, the second sensor, and the user interface, wherein the controller comprises a computing device programmed to perform operations comprising:
obtaining a baseline activity profile;
detecting, using the first sensor during a first period of time, a first signal relating to motion of the body segment of the person;
determining, based on the first signal and the baseline activity profile, that a motor activity of the person during the first period of time differs from the baseline activity profile;
responsive to determining that the motor activity of the person during the first period of time differs from the baseline activity profile, (i) using the user interface to provide a prompt to perform a motor task, and (ii) activating the second sensor to measure one or more properties related to performing the motor task and to output a second signal based on measurement of the one or more properties;
and
after using the user interface to provide the prompt, using the second sensor to detect the second signal related to performance of the motor task.

8 more elements

A non-transitory computer-readable medium having stored thereon instructions executable by at least one processor to perform operations comprising:

obtaining a baseline activity profile;
detecting, using a first sensor of a device during a first period of time, a first signal relating to motor activity of a person;
determining, based on the first signal and the baseline activity profile, that the motor activity of the person during the first period of time differs from the baseline activity profile;
responsive to determining that the motor activity of the person during the first period of time differs from the baseline activity profile, (i) using a user interface of the device to provide a prompt to perform a motor task and (ii) activating the user interface to measure one or more properties related to performing the motor task and to output a second signal based on measurement of the one or more properties;
and
after using the user interface to provide the prompt, operating the user interface to detect the second signal related to the motor task.

3 more elements

Dependencies are inferred from the claim text.

Facts

Application: 17/543,448Filed 6 Dec 2021 · continuation
Priority: 7 Apr 2017
Published: US 2022/0165413 A126 May 2022
Granted: 11 Jul 2023
Term ends: Not estimatedThe source records don’t support an estimate.

Classification8 codes

G16H 40/67
For the operation of medical equipment or devices: for remote operation
G16H 20/30
ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient…:…
G16H 40/63
For the operation of medical equipment or devices: for local operation
G16H 50/20
ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or…: for…