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US 11,697,793 B2Granted
Compositions and methods of making and using protein-functionalized hydrogels
AssigneeWashington University
InventorsAmit Pathak, Bapi Sarker
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Abstract
Among the various aspects of the present disclosure is the provision of a hydrogel-based substrate comprising an aldehyde-containing component, such as N-ethanal acrylamide. The hydrogel component allows for functionalization of a hydrogel through conjugation of proteins (e.g., collagen) to the hydrogel in the absence of a post hoc crosslinking component.
Claims7
A polyacrylamide (PA) hydrogel substrate comprising an aldehyde-containing acrylamide for protein functionalization, wherein protein functionalization of the PA hydrogel enables protein fiber formation of a tunable protein fiber length.
Dependencies are inferred from the claim text.