Anti-IL31 antibodies for veterinary use
AssigneeKindred Biosciences, Inc.
InventorsShyr Jiann Li, Lam Nguyen, Hangjun Zhan
Life of this patent
Estimating the term…
Abstract
Provided are various embodiments relating to anti-IL31 antibodies binding to canine IL31. Such antibodies can be used in methods to treat IL31-induced conditions in companion animals, such as canines, felines, and equines.
Claims20
An isolated nucleic acid encoding an antibody that binds to canine IL31, wherein the antibody comprises (a) CDR-H1 comprising the amino acid sequence of SEQ ID NO:
- 1;
- (b) CDR-H2 comprising the amino acid sequence of SEQ ID NO:
- 2;
- (c) CDR-H3 comprising the amino acid sequence of SEQ ID NO:
- 3;
- (d) CDR-L1 comprising the amino acid sequence of SEQ ID NO:
- 8;
- (e) CDR-L2 comprising the amino acid sequence of SEQ ID NO:
- 9;
- and (f) CDR-L3 comprising the amino acid sequence of SEQ ID NO:
- 10.
An isolated nucleic acid encoding an antibody that binds to canine IL31, wherein the antibody comprises a variable light chain amino acid sequence of SEQ ID NO:
- 16 and a variable heavy chain amino acid sequence of SEQ ID NO:
- 15.
An isolated nucleic acid encoding an antibody that binds to canine IL31, wherein the antibody comprises a light chain amino acid sequence of SEQ ID NO:
- 21 and a heavy chain amino acid sequence of SEQ ID NO:
- 17, SEQ ID NO:
- 18, SEQ ID NO:
- 19, or SEQ ID NO:
- 20.
Dependencies are inferred from the claim text.