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US 11,696,969 B2Granted
Ethylene oxide treatment indicator, label and method of use
AssigneeGlobal Life Sciences Solutions Operations UK Ltd
InventorPeter James Tatnell
Life of this patent
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Abstract
The present invention provides an indicator useful in confirming successful sterilisation and/or nucleic acid decontamination by ethylene oxide (EtO) treatment. The invention also provides a label comprising said indicator and methods for use of the indicator and label in a method of EtO treatment.
Claims11
A method to confirm successful EtO exposure wherein said method comprises:
- (a) exposing an article to EtO for a defined period of time wherein said article comprises an indicator;
- (b) inspecting a colour of said indicator following step (a);
- wherein said indicator comprises a solid support, a dye, and one or more nucleic acid stabilization chemicals, wherein said one or more nucleic acid stabilisation chemicals comprises a chaotrope, wherein the solid support is treated with the dye to form a chemical bond between the dye and the solid support, wherein the dye is selected from the group consisting of—
- (i) Bromophenol Red,
- (ii) Bromocresol Purple,
- (iii) Bromothymol Blue,
- (iv) Bromoxylenol Blue,
- (v) Chlorophenol Red,
- (vi) m-Cresol Purple,
- (vii) Cresol Red,
- (viii) Neutral Red,
- (ix) Nitrazine Yellow,
- (x) Rosolic Acid,
- (xi) Mordant Blue 9, and
- (xii) Ruthenium Red.
12 more elements
Dependencies are inferred from the claim text.