Single protein-encapsulated pharmaceutics for enhancing therapeutic effects
AssigneeSunstate Biosciences, LLC
InventorChangjun Yu
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Abstract
The invention provides compositions comprising a single protein having one or more molecules of a pharmaceutical agent tightly bound therein. The compositions are useful to decrease the toxicity and/or to widen the therapeutic window of the pharmaceutical agent. The invention also provides methods for preparing such a composition.
Claims3
A composition, comprising a single protein selected from the group consisting of an albumin, a globulin, and a fibrinogen, having tightly bound therein, a plurality of molecules of doxorubicin.
A composition, comprising the single protein human albumin having tightly bound therein a plurality of molecules of doxorubicin.
Dependencies are inferred from the claim text.