Compositions containing exosome carrying NF-κB inhibitors and methods of using thereof
AssigneesIlias Biologics Inc., Ilias Therapeutics, Inc.
InventorsChulhee Choi, Kyungsun Choi, Ramkumar Menon
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Abstract
The present invention is related to compositions containing extracellular vesicles (exosomes) and methods of using the same for increasing lifespan of fetus, viability of fetus, or viability of newborn, for treating inflammation in uterus and/or fetus, for delaying preterm birth, or for treating a condition related to inflammation in uterus and/or fetus, wherein the extracellular vesicles comprising a nuclear factor kappa beta (NF-κB) inhibitor and a photo-specific binding protein.
Claims21
A method for increasing lifespan of fetus, viability of fetus, or viability of newborn, for treating inflammation in uterus fetus, for delaying preterm birth, or for treating a condition related to inflammation in uterus and/or fetus during pregnancy comprising:
- administering a composition comprising extracellular vesicles comprising a nuclear factor kappa beta (NF-κB) inhibitor to a subject in need thereof.
A method of changing inflammatory profile of fetal inflammatory cells or fetal inflammatory cell migration comprising:
- administering a composition comprising extracellular vesicles comprising a nuclear factor kappa beta (NF-κB) inhibitor to a subject in need thereof.
Dependencies are inferred from the claim text.