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US 11,696,933 B2Granted
HLA-restricted VCX/Y peptides and T cell receptors and use thereof
AssigneeBoard of Regents, The University of Texas System
InventorsCassian Yee, Ke Pan
Life of this patent
Estimating the term…
Abstract
Provided herein are tumor-antigen VCX/Y specific peptides and engineered VCX/Y specific T cell receptors. Also provided herein are methods of generating VCX/Y-specific immune cells and their use for the treatment of cancer. In addition, the VCX/Y-specific peptides may be used as a vaccine.
Claims34
An engineered T cell receptor (TCR) comprising an alpha chain CDR3 of SEQ ID NO:2 and a beta chain CDR3 of SEQ ID NO:3 or an alpha chain CDR3 of SEQ ID NO:
- 19 and a beta chain CDR3 of SEQ ID NO:20.
Dependencies are inferred from the claim text.