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US 11,696,902 B2Granted
Method of initiating and escalating sotalol hydrochloride dosing
AssigneeAltaThera Pharmaceuticals LLC
InventorsJohn Somberg, Brandon Ira Kashfian, Janos Molnar
Life of this patent
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Abstract
This disclosure provides a method of safely and rapidly initiating or escalating oral sotalol therapy by administering an intravenous dosage of sotalol followed by oral sotalol twice daily.
Claims5
A method of initiating oral sotalol hydrochloride therapy comprising:
- identifying a subject as naïve to sotalol, having symptomatic atrial fibrillation or atrial flutter, and currently in sinus rhythm;
- administering to the subject a single intravenous (IV) dosage of sotalol hydrochloride, over a period of 1 hour, wherein the single IV dosage comprises an amount of sotalol hydrochloride in the range of 116-141 mg;
- after completion of the single IV dosage of sotalol hydrochloride, administering a first oral dosage of sotalol hydrochloride in the amount of 120 mg.
Dependencies are inferred from the claim text.