US 11,693,190 B2Granted

Indexing signal detecting module

AssigneeGen-Probe Incorporated

InventorsNorbert D. Hagen, David Opalsky

Life of this patent

Estimating the term…

Loading patent…

Abstract

An apparatus for detecting an emission signal from each of a plurality of emission signal sources includes one or more excitation sources configured to generate an excitation light of an excitation wavelength and one or more associated emission detectors configured to detect light of an emission wavelength. A transmission fiber is associated with each of the emission signal sources. A carrier is configured to move the one or more excitation sources and the one or more emission detectors relative to the transmission fibers to sequentially place each emission detector and associated excitation source in an operative position with respect to each transmission fiber. Each transmission fiber transmits both the excitation light from the excitation source and the corresponding emission light to the associated emission detector.

Claims20

Dependent claims

An apparatus for detecting an emission signal from each of a plurality of emission signal sources, wherein each emission signal source comprises a substance that emits light of a predetermined emission wavelength when subjected to an excitation signal of a predetermined excitation wavelength, said apparatus comprising:

one or more excitation sources configured to generate an excitation signal that is directed at an emission signal source, wherein each excitation source is configured to generate an excitation light of a predetermined excitation wavelength;
one or more emission detectors, each emission detector being associated with at least one excitation source and being configured to detect an emission signal emitted by each emission signal source and excited by the excitation signal generated by the associated excitation source, wherein each associated emission detector is configured to detect light of a predetermined emission wavelength;
a transmission fiber associated with each of the emission signal sources;
and
a carrier configured to move each of the one or more excitation sources and the associated emission detector relative to the transmission fibers to sequentially place each emission detector and associated excitation source in an operative position with respect to one transmission fiber, wherein each transmission fiber transmits both the excitation light from the operatively-positioned excitation source and the corresponding emission light to the operatively-positioned associated emission detector.

2 more elements

A method of detecting an emission signal from each of a plurality of emission signal sources, the method comprising:

generating with each of a plurality of excitation sources an excitation signal, wherein each of the excitation sources is configured to generate an excitation light of a different predetermined excitation wavelength;
detecting an emission signal with each of a plurality of emission detectors, wherein each emission detector is associated with at least one of the excitation sources, wherein each emission signal is emitted by an emission signal source of the emission sources when excited by the excitation signal generated by the associated excitation source, and wherein each of the emission detectors is configured to detect light of a different predetermined emission wavelength;
and
moving each of the excitation sources and the associated emission detector relative to a plurality of transmission fibers, wherein each of the plurality of emission signal sources is in optical communication with a single one of the transmission fibers, to sequentially place each emission detector and the associated excitation source in an operative position with respect to one of the transmission fibers, wherein each transmission fiber transmits both the excitation light from the operatively-positioned excitation source and the corresponding emission light to the operatively-positioned associated emission detector.

1 more element

Dependencies are inferred from the claim text.

Facts

Application: 17/144,880Filed 8 Jan 2021 · continuation
Priority: 14 Mar 2013
Published: US 2021/0157060 A127 May 2021
Granted: 4 Jul 2023
Term ends: Not estimatedThe source records don’t support an estimate.

Classification12 codes

G02B 6/3668
2D cross sectional arrangements of the fibres: with conversion in geometry of the cross section
G01N 21/253
Colorimeters; Construction thereof: for batch operation, i.e. multisample apparatus
G01N 21/6452
Specially adapted constructive features of fluorimeters: individual samples arranged in a regular 2D-array, e.g. multiwell plates
G02B 6/06
Formed by bundles of fibres: the relative position of the fibres being the same at both ends, e.g. for transporting images

Family

Application61/782,340Us provisional application · filed 14 Mar 2013
Application14/200,460Parent of this division · filed 7 Mar 2014
Application15/287,358Parent of this division · filed 6 Oct 2016
US 9,465,161 B2Parent of this division · filed 11 Oct 2016
Application16/179,609Parent of this continuation · filed 2 Nov 2018
US 10,120,136 B2Parent of this division · filed 6 Nov 2018
US 2021/0157060 A1Pre-grant publication · published 27 May 2021
US 10,890,720 B2Parent of this continuation
Application16/179,609Parent of this division
US 2014/0263984 A1Published application
US 2017/0023743 A1Published application
US 2019/0079248 A1Published application
US 11,693,190 B2This patent

From the US filing history. Foreign family members aren’t listed.