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US 11,692,996 B2Granted
Device for detection of cellular stress
AssigneesTrustees of Boston University, Northwestern University
InventorsJi-Xin Cheng, Junjie Li, Yuying Tan, Daniela Matei, Guangyuan Zhao
Life of this patent
Estimating the term…
Abstract
Disclosed is an assay for determining resistance in a target cell or tissue to a therapy associated with cellular stress using chemical microscopy and high-throughput single cell analysis to determine functional metabolic alteration, including determining metabolic reprogramming in a target cell or tissue to a therapy associated with cellular stress, and methods of using the assays.
Claims20
An assay for determining resistance in a target cell or tissue to a therapy associated with cellular stress, comprising,
- measuring with chemical microscopy a functional metabolic change in the target cell or tissue, and
- determining a metabolic index of resistance in the target cell or tissue to the therapy.
Dependencies are inferred from the claim text.