Fast diagnosis and personalized treatments for acne
AssigneeThe Regents of the University of California
InventorsHuiying Li, Shuta Tomida, Robert L. Modlin, Jeffery F. Miller, Sorel T. Fitz-Gibbon
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Abstract
Methods of diagnosing and treating patients afflicted with acne, including diagnosing one as having acne if the individual possesses RT4, RT5, RT7, RT8, RT9, or RT10. Methods for treating acne include administering an effective amount of a drug specifically targeting RT4, RT5, RT7, RT8, RT9, or RT10, such as small molecules, antisense molecules, siRNAs, biologics, antibodies, phages, vaccines, or combination thereof.
Claims8
A method for treating an individual suffering from acne, comprising:
- administering to the individual an effective amount of a probiotic that comprises at least one strain of P. acnes that is associated with healthy or normal skin based on its 16S rDNA.
A method for treating an individual suffering from acne, comprising:
- administering to the individual an effective amount of a metabolite produced by a strain of P. acnes that is associated with healthy or normal skin,
- wherein said metabolite is selected from the group consisting of bacterial culture supernatant, cell lysate, proteins, nucleic acids, lipids, and other bacterial molecules.
Dependencies are inferred from the claim text.