Genetically modified fungal cells for overexpression of an acetyl-CoA carboxylase and a pyruvate carboxylase
AssigneeMelt & Marble AB
InventorsAnastasia Krivoruchko, Jens Nielsen, Florian David, Tao Yu
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Abstract
A fungal cell is capable of producing high levels of fatty acids and fatty acid-derived products. The fungal cell comprises at least one modification to the endogenous fatty acid metabolism.
Claims24
A fungal cell for the production of fatty acids and/or fatty acid-derived products, wherein said fungal cell is genetically modified for overexpression of an endogenous acetyl-CoA carboxylase and an endogenous pyruvate carboxylase, and wherein said fungal cell has an increased production of fatty acids and/or fatty acid-derived products over a wild-type fungal cell that is not genetically modified for overexpression of said endogenous acetyl-CoA carboxylase and said endogenous pyruvate carboxylase.
Dependencies are inferred from the claim text.