Back to results
US 11,692,181 B2Granted
Esterases and uses thereof
AssigneeCarbios
InventorsIsabelle Andre, Vincent Tournier, Alexandre Gilles, Sophie Duquesne
Life of this patent
Estimating the term…
Abstract
The present invention relates to novel esterases, more particularly to esterase variants having improved activity and/or improved thermostability compared to the esterase of SEQ ID NO: 1 and the uses thereof for degrading polyester containing material, such as plastic products. The esterases of the invention are particularly suited to degrade polyethylene terephthalate, and material containing polyethylene terephthalate.
Claims22
An esterase which (i) comprises an amino acid sequence consisting of the amino acid sequence set forth in SEQ ID NO:
- 1, (ii) with one to fourteen amino acid substitutions selected from the group consisting of A17T, T27S, S48T, L82I, F90L, Y92F, G135A, A140S, N143I, S145T, A149G, S164P, V167Q, S206T, or N213P wherein the positions are numbered by reference to the amino acid sequence set forth in SEQ ID NO:
- 1, and (iii) exhibits increased polyester degrading activity and/or increased thermostability compared to an esterase of SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.