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US 11,692,041 B2Granted
Antibody molecules which bind CD45
AssigneeUcb Biopharma Srl
InventorsHelene Margaret Finney, Stephen Edward Rapecki, Kerry Louise Tyson, Michael John Wright
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Abstract
The present disclosure relates to constructs, such as antibody molecules comprising a binding domain specific to CD45, said binding domain comprising SEQ ID NO: 1, 2, 3 and/or SEQ ID NO: 4, 5 and 6. The disclosure also extends to pharmaceutical compositions comprising said constructs and use of the constructs/compositions in treatment.
Claims14
An antibody molecule comprising a binding domain specific to human CD45 comprising a heavy chain variable domain (VH) comprising:
- a CDRH1 comprising SEQ ID NO:
- 15;
- and a CDRH2 comprising SEQ ID NO:
- 29;
- and a CDRH3 comprising SEQ ID NO:
- 34;
- and a light chain variable domain (VL) comprising:
- a CDRL1 comprising SEQ ID NO:
- 41;
- a CDRL2 comprising SEQ ID NO:
- 48;
- and a CDRL3 comprising SEQ ID NO:
- 59.
10 more elements
Dependencies are inferred from the claim text.