US 11,692,011 B2Granted

Hepatitis B virus-derived polypeptide and anti-viral use thereof

AssigneeSeoul National University R&Db Foundation

InventorsBum Joon Kim, Yu Min Choi, Hong Kim

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Abstract

A hepatitis B virus-derived polypeptide exhibits anti-viral effects not only on HIV-1 and HBV but also on all viruses by increasing the expression of type I interferon. The hepatitis B virus-derived polypeptide has a synergistic effect when co-administered with a conventional anti-viral agent. The hepatitis B virus-derived polypeptide is effectively usable in the treatment of virus-related diseases such as AIDS or liver diseases.

Claims19

Dependent claims

An isolated polypeptide comprising an end-capping modification consisting of any one amino acid sequence selected from the group consisting of SEQ ID NO:

1, SEQ ID NO:
2, and SEQ ID NO:
3.

Dependencies are inferred from the claim text.

Facts

Application: 17/090,485Filed 5 Nov 2020 · continuation in part
Priority: KR 10-2018-00530399 May 2018
Published: US 2021/0054029 A125 Feb 2021
Granted: 4 Jul 2023
Term ends: Not estimatedThe source records don’t support an estimate.

Classification20 codes

A61P 31/18
For RNA viruses: for HIV
C07K 14/005
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from viruses
A61K 31/708
Containing purines, e.g. adenosine, adenylic acid: having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
A61K 38/162
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from virus

Family

PCT/KR2019/005302Parent of this continuation-in-part · filed 3 May 2019
US 2021/0054029 A1Pre-grant publication · published 25 Feb 2021
US 11,692,011 B2This patent

From the US filing history. Foreign family members aren’t listed.

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