Functionalized n-acetylgalactosamine analogs

A compound having the Formula (IId):

• or a pharmaceutically acceptable salt thereof, wherein
• each of L1a, L1b, L1c, L2a, L2b, L2c, L3a, L3b, and L3c is independently a bond, —C(═O)—, —C(═S)—, —S(═O)2—, —C(═O)NR9—, —C(═S)NR9—, —C(═O)O—, —C(═S)O—, —NR9C(═O)NR9—, —NR9C(═S)NR9—, —OP(═O)(OH)O—, —OP(═S)(OH)O , —O—, —S—, —NR9—, optionally substituted C1-10 alkylene, optionally substituted C6-10 arylene, optionally substituted C3-10 cycloalkylene, optionally substituted 5-10 membered hetetroarylene, optionally substituted 5 to 10 membered heterocyclylene, or optionally substituted 2 to 15 membered heteroalkylene wherein one or more carbon atoms are replaced with C(═O), O, S or N, provided that at least one of L1a, L1b and L1c is not a bond, at least one of L2a, L2b and L2c is not a bond, and at least one of L3a, L3b and L3c is not a bond;
• L5 is absent, optionally substituted C1-10 alkylene, or optionally substituted 2 to 15 membered heteroalkylene wherein one or more carbon atoms are replaced with C(═O), O, S or N;
• each R9 is independently hydrogen, unsubstituted C1-6 alkyl, substituted C1-6 alkyl, or an amino protecting group;
• each of X1, X2 and X3 is —OCH2— or —NHCH2—, or each of X1 and X3 is —C(═O)CH2CH2—, and X2 is —C(═O)CH2—;
• Y2 is NH, *NH(C═O), O or absent, the asterisk * indicates that Y2 is connected to L5 through the nitrogen atom of Y2;
• and
• R6 is —C(═O)CH2CH2C(═O)OH or