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US 11,691,992 B2Granted
Oxaborole analogs and uses thereof
AssigneesAnacor Pharmaceuticals, Inc., The Government of the United States, as represented by the Secretary of the Army
InventorsRobert Toms Jacobs, Yang Liu, Richard J. Sciotti, Jason D. Speake, Gavin Alistair Whitlock, Paul Alan Glossop, Charles Eric Mowbray, Delphine Françoise Monique Launay, Stephen John Robinson
Life of this patent
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Abstract
This application describes compounds, compositions, and methods which are useful in treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a parasite.
Claims20
A compound of formula I:
- or a pharmaceutically acceptable salt thereof, wherein:
- R1a is hydrogen or C1-6-aliphatic;
- R1b is hydrogen or C1-6-aliphatic;
- wherein R1a and R1b are optionally taken together to form an optionally substituted 3- to 6-membered carbocyclic ring;
- Ring A is triazolyl substituted with an R2 group and an R3 group;
- R2 is hydrogen or an optionally substituted group selected from C1-6 aliphatic and 3-6 membered carbocyclyl;
- R3 is an optionally substituted group selected from phenyl, C1-6 aliphatic, 3-8 membered carbocyclyl, and 5-6 membered heteroaryl containing 1-3 heteroatoms independently selected from nitrogen, oxygen, and sulfur.
4 more elements
Dependencies are inferred from the claim text.