Biological chip, manufacturing method thereof, operation method thereof, and biological detection system
AssigneeBoe Technology Group Co., Ltd.
InventorsZhihong Wu, Zijian Zhao
Life of this patent
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Abstract
A biological chip, a manufacturing method thereof, an operation method thereof, and a biological detection system are provided. The biological chip includes a base substrate and a plurality of working units. The plurality of the working units are arranged on the base substrate; each of the working units includes a working element configured to be in contact with a target substance; and the working element includes a metal electrode and an electric-field-controllable surface modification layer on a surface of the metal electrode.
Claims19
A biological chip, comprising:
- a base substrate;
- a plurality of working units, arranged on the base substrate;
- a flow channel defining layer, arranged on the base substrate;
- wherein each of the working units comprises a working element configured to be in contact with a target substance, and the working element comprises a metal electrode and an electric-field-controllable surface modification layer on a surface of the metal electrode away from the base substrate and facing the target substance;
- the flow channel defining layer comprises a flow channel, and a fluid comprising the target substance reaches at least one of the plurality of the working units through the flow channel.
A method of manufacturing a biological chip, comprising:
- forming a plurality of working units on a base substrate, wherein each of the working units comprises a working element for contacting with a target substance, and the working element comprises a metal electrode and an electric-field-controllable surface modification layer formed on a surface of the metal electrode away from the base substrate and facing the target substance;
- forming a flow channel defining layer on the base substrate, wherein the flow channel defining layer comprises a flow channel, and a fluid comprising the target substance reaches at least one of the plurality of the working units through the flow channel;
- applying a control signal to a selected working unit of the plurality of the working units, and forming a control electric field through the working element of the selected working unit, wherein the control electric field controls a property of the electric-field-controllable surface modification layer of the working element of the selected working unit to control an operation of a fluid including the target substance.
Dependencies are inferred from the claim text.