Platform and method for multi-variable screening

A method for conducting multi-variable combinational interactions, comprising the steps of:

• providing an array of multiplexing chambers in a body, the body including:
• common well communicating with each multiplexing chamber of the array of multiplexing chambers;
• and
• a plurality of variable wells, each of variable wells communicating with at least one multiplexing chamber of the array of multiplexing chambers;
• loading the common well with a first variable;
• loading different variables in each of the plurality of variable wells;
• and
• observing the interaction of the first variable with at least one of the different variables in each multiplexing chamber of the array of multiplexing chambers;
• wherein each of the multiplexing chambers of the array of multiplexing chambers has a triangular configuration.

A method for conducting multi-variable combinational interactions, comprising the steps of:

• providing an array of multiplexing chambers in a body, the body including:
• a common well communicating with each multiplexing chamber of the array of multiplexing chambers;
• and
• a plurality of variable wells, each of variable wells communicating with at least one multiplexing chamber of the array of multiplexing chambers;
• loading the common well with a first variable;
• loading different variables in each of the plurality of variable wells;
• and
• observing the interaction of the first variable with at least one of the different variables in each multiplexing chamber of the array of multiplexing chambers;
• wherein each of the multiplexing chamber of the array of multiplexing chambers has an equilateral triangular configuration.

A method for conducting multi-variable combinational interactions, comprising the steps of:

• providing an array of multiplexing chambers in a body, the body including,
• a common well communicating with each multiplexing chamber of the array of multiplexing chambers;
• and
• a plurality of variable wells, each of variable wells communicating with at least one multiplexing chamber of the array of multiplexing chambers;
• loading the common well with a first variable;
• loading different variables in each of the plurality of variable wells;
• and
• observing the interaction of the first variable with at least one of the different variables in each multiplexing chamber of the array of multiplexing chambers;
• wherein the array of multiplexing chambers is defined by six multiplexing chambers, each multiplexing chamber including:
• first, second and third vertices, wherein the common well is located at the first vertex of each of the multiplexing chambers;
• and
• each variable well is located at the second vertex of each of the multiplexing chambers and at the third vertex of an adjacent multiplexing chamber such that each variable well communicates with a corresponding one of the multiplexing chambers and with the adjacent multiplexing chamber.

A method for conducting multi-variable combinational interactions, comprising the steps of:

• providing an array of multiplexing chambers in a body, the body including,
• a common well communicating with each multiplexing chamber of the array of multiplexing chambers;
• and
• a plurality of variable wells, each of variable wells communicating with at least one multiplexing chamber of the array of multiplexing chambers,
• loading the common well with a first variable;
• loading different variables in each of the plurality of variable wells;
• and
• observing the interaction of the first variable with at least one of the different variables in each multiplexing chamber of the array of multiplexing chambers;
• wherein each multiplexing chamber of the array of multiplexing chambers communicates with the first variable and two different variables, the combination of the first variable and two different variables communicating with each multiplexing chamber being different than the combination of the first variable and two different variables communicating with each of the other multiplexing chambers of the array of multiplexing chambers.